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Chest pain

Chest pain: when to worry and what you need to know

Chest pain is one of the most common—and at the same time most feared—symptoms. It doesn’t always mean a “heart attack,” but it always deserves attention: the chest contains the heart, lungs, major vessels, esophagus, muscles, and nerves, and each of these structures can generate pain with different characteristics.

On this page you will find useful information to recognize the various types of chest pain, understand when to consult a doctor, and learn the typical features of cardiac-related chest pain.

Why chest pain is not all the same

Chest pain can originate from many different causes. The main causes can be divided into several major groups:

1. Cardiac causes

  • Stable angina

  • Unstable angina / Acute myocardial infarction

  • Pericarditis

  • Aortic dissection

2. Pulmonary causes

  • Pulmonary embolism

  • Pneumothorax

  • Pneumonia

  • Pleurisy

3. Gastrointestinal causes

  • Gastroesophageal reflux (GERD)

  • Esophageal spasms

  • Gastritis or ulcer

4. Musculoskeletal causes

  • Costochondritis

  • Muscle strains or contractures

  • Trauma to the chest wall

5. Neurological or psychogenic causes

  • Intercostal neuralgia

  • Panic attacks

  • Acute anxiety

How to distinguish cardiac chest pain from other types of chest pain

Cardiac pain has some relatively typical characteristics.


Below are the most important elements that help physicians make a diagnosis.

Characteristics of cardiac (anginal) pain

Quality

  • Sensation of tightness, pressure, heaviness

  • Sometimes described as a “vise,” “weight on the chest,” or “stone on the chest”

Location

  • Retrosternal area or center of the chest

Radiation

Often spreads to:

  • left arm or both arms

  • jaw

  • neck

  • shoulders

  • back

Duration

  • Typically lasts more than a few minutes; it is not a brief, fleeting pain

  • Does not change with breathing or movement

Triggers

  • Physical exertion

  • Emotional stress

  • Intense cold

  • Heavy meals

Relieving factors

  • Rest

  • Sublingual nitroglycerin (in known cases of angina)

When chest pain is not typically cardiac

Muscular or osteoarticular pain

  • Worsens with movement or when pressing on the painful spot

  • Sharp or related to breathing

Pain from reflux or gastrointestinal disorders

  • Burning sensation behind the sternum

  • Related to meals

  • Improves with antacids

Pleuritic or pulmonary pain

  • Sudden sharp pain that worsens with deep breathing

  • May be accompanied by cough or fever

Anxiety-related pain or panic attacks

  • Sensation of tightness associated with rapid breathing, trembling, or intense fear

  • ECG and cardiac tests are often normal

When to seek immediate medical attention

Call emergency services (911/112 depending on your country) or go to the emergency department if chest pain is:

  • Sudden, severe, or associated with cold sweating

  • Accompanied by shortness of breath, nausea, fainting, or palpitations

  • Radiating to the arm, jaw, or back

  • Not improving after a few minutes of rest

  • Present in a patient with cardiovascular risk factors (hypertension, diabetes, high cholesterol, smoking, family history)

Diagnosis: how the cause of chest pain is identified

Doctors always assess chest pain using a structured approach:

1. Medical history

  • Characteristics of the pain

  • Triggering factors

  • Medical history and risk factors

2. Physical examination

  • Blood pressure, heart rate, oxygen saturation

  • Cardiac and lung auscultation

  • Evaluation of the chest wall

3. Diagnostic tests

  • Electrocardiogram (ECG)

  • Blood tests (troponin)

  • Chest X-ray

  • Echocardiogram

  • Stress test or coronary CT when indicated

Conclusion

Chest pain should never be ignored: recognizing its characteristics can help patients understand when to seek prompt medical attention. At the same time, many forms of chest pain are not heart-related and can be managed safely.

If you have doubts or recurrent symptoms, talk to your cardiologist: a targeted specialist evaluation is always the best way to determine the origin of the pain and choose the most appropriate diagnostic pathway.


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© 2025 Dr. Alessandro Durante, cardiologo

Iscritto all'Ordine Provinciale dei Medici Chirurghi e degli Odontoiatri di Milano al n. 41321

Comunicazione inviata all'Ordine dei Medici in data 11/08/2014

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