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Myocardial Infarction

A myocardial infarction—commonly called heart attack—occurs when a coronary artery becomes blocked and prevents blood from reaching a portion of the heart muscle. Without oxygen and nutrients, the heart muscle begins to be damaged. Prompt treatment is essential: the sooner blood flow is restored, the better the chances of limiting damage and saving heart muscle.

Why does a heart attack happen?

Most heart attacks occur because of atherosclerosis, a process in which cholesterol and fatty deposits (plaques) build up inside the coronary arteries.
If one of these plaques ruptures, a blood clot can form and suddenly block the artery.

Other, less common causes include:

  • Spasm of a coronary artery (coronary vasospasm)

  • Spontaneous tearing of the artery wall (SCAD)

  • Embolism (a clot coming from another area of the body)

Recognizing a Heart Attack: Main Symptoms

Typical symptoms include:

  • Pressure, tightness, or pain in the chest, often spreading to the left arm, shoulder, neck, jaw, or back

  • Shortness of breath

  • Cold sweats

  • Nausea or vomiting

  • Sudden fatigue, weakness, or light-headedness

⚠️ A heart attack is a medical emergency. Call emergency services immediately if symptoms appear.

Not everyone experiences “classic” chest pain. Women, older adults, and people with diabetes may have milder or atypical symptoms, such as:

  • Indigestion-like discomfort

  • Sudden fatigue

  • Breathlessness without chest pain

Types of Myocardial Infarction

Heart attacks are not all the same. The diagnosis is based on symptoms, ECG changes, and blood tests (troponin).

1. STEMI (ST-Elevation Myocardial Infarction)

  • The coronary artery is completely blocked.

  • Requires immediate reopening of the artery, ideally within 90 minutes from first medical contact.

  • Urgency is critical: “Time is muscle.”

2. NSTEMI (Non-ST-Elevation Myocardial Infarction)

  • The artery is partially blocked.

  • Damage occurs but usually to a smaller portion of the heart.

  • Treatment is urgent, but timing is guided by risk assessment.

3. MINOCA (Myocardial Infarction with Non-Obstructive Coronary Arteries)

  • Heart attack caused by conditions other than classic plaque rupture, such as spasm or microcirculation dysfunction.

  • More common in younger patients and women.

How is a Heart Attack Treated?

The main goal is to restore blood flow to the heart as quickly as possible.

 

Emergency Treatments

Depending on the type of infarction:

  • Primary angioplasty (PCI):
    A small balloon is inserted to open the blocked artery, followed by the placement of a stent.

  • Thrombolytic therapy (fibrinolysis):
    Medication is given intravenously to dissolve the clot (used if angioplasty is not immediately available).

Medications

 

After the acute phase, patients typically receive medications to:

  • Prevent new clots (antiplatelet therapy)

  • Reduce cardiac workload (beta-blockers)

  • Lower cholesterol and stabilize plaques (statins)

  • Help heart function and protect arteries (ACE inhibitors / ARBs)

Cardiac Rehabilitation

A structured program of exercise, lifestyle support, and risk factor management. It improves quality of life and reduces the risk of future events.

 

Prevention: What You Can Do

You can significantly reduce the risk of recurrence by managing the main risk factors:

  • Control blood pressure, cholesterol, and blood sugar

  • Quit smoking

  • Maintain a healthy weight

  • Follow a Mediterranean-style diet

  • Exercise regularly, as advised by your cardiologist

A heart attack is a serious but treatable condition. Recognizing symptoms early and getting immediate medical care can save heart muscle—and save lives. After treatment, ongoing follow-up and rehabilitation are essential to reduce the risk of recurrence and support long-term heart health.

© 2025 Dr. Alessandro Durante, cardiologo

Iscritto all'Ordine Provinciale dei Medici Chirurghi e degli Odontoiatri di Milano al n. 41321

Comunicazione inviata all'Ordine dei Medici in data 11/08/2014

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