Alessandro Durante MD
Cardiologist
Myocardial Infarction
A myocardial infarction—commonly called heart attack—occurs when a coronary artery becomes blocked and prevents blood from reaching a portion of the heart muscle. Without oxygen and nutrients, the heart muscle begins to be damaged. Prompt treatment is essential: the sooner blood flow is restored, the better the chances of limiting damage and saving heart muscle.
Why does a heart attack happen?
Most heart attacks occur because of atherosclerosis, a process in which cholesterol and fatty deposits (plaques) build up inside the coronary arteries.
If one of these plaques ruptures, a blood clot can form and suddenly block the artery.
Other, less common causes include:
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Spasm of a coronary artery (coronary vasospasm)
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Spontaneous tearing of the artery wall (SCAD)
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Embolism (a clot coming from another area of the body)
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Recognizing a Heart Attack: Main Symptoms
Typical symptoms include:
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Pressure, tightness, or pain in the chest, often spreading to the left arm, shoulder, neck, jaw, or back
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Shortness of breath
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Cold sweats
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Nausea or vomiting
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Sudden fatigue, weakness, or light-headedness
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⚠️ A heart attack is a medical emergency. Call emergency services immediately if symptoms appear.
Not everyone experiences “classic” chest pain. Women, older adults, and people with diabetes may have milder or atypical symptoms, such as:
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Indigestion-like discomfort
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Sudden fatigue
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Breathlessness without chest pain
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Types of Myocardial Infarction
Heart attacks are not all the same. The diagnosis is based on symptoms, ECG changes, and blood tests (troponin).
1. STEMI (ST-Elevation Myocardial Infarction)
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The coronary artery is completely blocked.
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Requires immediate reopening of the artery, ideally within 90 minutes from first medical contact.
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Urgency is critical: “Time is muscle.”
2. NSTEMI (Non-ST-Elevation Myocardial Infarction)
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The artery is partially blocked.
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Damage occurs but usually to a smaller portion of the heart.
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Treatment is urgent, but timing is guided by risk assessment.
3. MINOCA (Myocardial Infarction with Non-Obstructive Coronary Arteries)
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Heart attack caused by conditions other than classic plaque rupture, such as spasm or microcirculation dysfunction.
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More common in younger patients and women.
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How is a Heart Attack Treated?
The main goal is to restore blood flow to the heart as quickly as possible.
Emergency Treatments
Depending on the type of infarction:
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Primary angioplasty (PCI):
A small balloon is inserted to open the blocked artery, followed by the placement of a stent. -
Thrombolytic therapy (fibrinolysis):
Medication is given intravenously to dissolve the clot (used if angioplasty is not immediately available).
Medications
After the acute phase, patients typically receive medications to:
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Prevent new clots (antiplatelet therapy)
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Reduce cardiac workload (beta-blockers)
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Lower cholesterol and stabilize plaques (statins)
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Help heart function and protect arteries (ACE inhibitors / ARBs)
Cardiac Rehabilitation
A structured program of exercise, lifestyle support, and risk factor management. It improves quality of life and reduces the risk of future events.
Prevention: What You Can Do
You can significantly reduce the risk of recurrence by managing the main risk factors:
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Control blood pressure, cholesterol, and blood sugar
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Quit smoking
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Maintain a healthy weight
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Follow a Mediterranean-style diet
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Exercise regularly, as advised by your cardiologist
A heart attack is a serious but treatable condition. Recognizing symptoms early and getting immediate medical care can save heart muscle—and save lives. After treatment, ongoing follow-up and rehabilitation are essential to reduce the risk of recurrence and support long-term heart health.